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Clinical-rehabilitative studies in collaboration with Auxilium

Many observational and interventional clinical studies are conducted in the cardiorespiratory and neurological areas of Auxilium Vitae, and mainly have as their object the analysis of the various aspects of rehabilitation outcomes, the physiology of exercise and the evaluation of techniques or devices, or particular treatment schemes. Some studies are conducted in the context of multicentric trials, sometimes supported by an unconditional contribution from companies producing electro-medical devices.

These studies represent a current research activity, to which the various professional figures of Auxilium Vitae contribute, which produces an important part of presentations at conferences and scientific publications, in addition to collaborations with important Italian and international rehabilitation centers.

Numerous clinical and pathophysiological studies are carried out in the cognitive-psychological field, with excellent results in particular in the evaluation of the patient with eminegligence and aphasia and in the rehabilitation of the comatose patient following a head injury.
Below there is a review of the current or recently completed cognitive-psychological studies, and some of the most recent and significant ISI publications produced.

Clinical-rehabilitative studies

Title Project Responsible Project Type
Randomized controlled clinical feasibility study of a respiratory rehabilitation program in patients with chronic respiratory disease following acute exacerbations (3472/2011) G. Vagheggini (Auxilium Vitae) Single Center, Spontaneous
Evaluation of the additional effect of non-invasive mechanical ventilation (VMN) during exercise in a cycle ergometer training program in patients with chronic respiratory failure in home nocturnal VMNI (667 / 2011CEC FSM) K. Foglio (FSM Lumezzane)
G. Vagheggini (Auxilium Vitae)
Multi center, Spontaneous, No Profit
Evaluation of swallowing disorders in subjects with difficulty weaning from mechanical ventilation A. Bartolini
M. Bilei (Auxilium Vitae)
Single Center, Observational, Spontaneous
Use of binaural beats as non-pharmacological premedication in elderly subjects to be subjected to major orthopedic surgery. Randomized controlled trial (NCT02712749) A. Tani (Anestesia e Rianimazione AVC)
F. Moretti (Auxilium Vitae) F. Tomaiuolo (Auxilium Vitae) G. Vagheggini (Auxilium V.)
Controlled randomized trial, Single Center, Spontaneous
Bibliography CLINICAL-REHABILITATIVE STUDIES
  1. Ambrosino N, Vitacca M, Dreher M, Isetta V, Montserrat JM, Tonia T, Turchetti G, Winck JC, Burgos F, Kampelmacher M, Vagheggini G; ERS Tele-Monitoring of Ventilator-Dependent Patients Task Force. Tele-monitoring of ventilator-dependent patients: a European Respiratory Society Statement. Eur Respir J. 2016 Sep;48(3):648-63. doi: 10.1183/13993003.01721-2015. Epub 2016 Jul 7.
  2. Mazzoleni S, Montagnani G, Vagheggini G, Buono L, Moretti F, Dario P, Ambrosino N. Interactive videogame as rehabilitation tool of patients with chronic respiratory diseases: preliminary results of a feasibility study. Respir Med. 2014 Oct;108(10):1516-24. doi: 10.1016/j.rmed.2014.07.004. Epub 2014 Jul 16.
  3. Vagheggini G, Mazzoleni S, Vlad Panait E, Navalesi P, Ambrosino N. Physiologic response to various levels of pressure support and NAVA in prolonged weaning. Respir Med. 2013 Nov;107(11):1748-54. doi: 10.1016/j.rmed.2013.08.013. Epub 2013 Aug 30.